Copyright © 2012 A. V. Wildemann et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
This paper introduces an approach for parameters identification of a
statistical predicting model with the use of the available individual data.
Unknown parameters are separated into two groups: the ones specifying
the average trend over large set of individuals and the ones describing the
details of a concrete person. In order to calculate the vector of unknown
parameters, a multidimensional constrained optimization problem is solved
minimizing the discrepancy between real data and the model prediction over
the set of feasible solutions. Both the individual retrospective data and factors
influencing the individual dynamics are taken into account. The application of
the method for predicting the movement of a patient with congenital motility disorders is considered.